The Halobacterium sp. NRC-1 Genome

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tbpD

Gene ID5163
Gene NametbpD
Annotationtranscription initiation factor IID
LocationpNRC100:128906←128349
Gene typeFunctional gene
GC content60.215
Hydropathicity0.067741935483871
DNA (558 bp, Edit)>tbpD|5163|128906|Rev|128349
atgagtacactcaccgacaccatccagatcgagaatgtcgtcgcctcgaccgatctcagccaggagttagccctcgagca
actcgcaactgacctccccggcgctgagtacaatcccggggattttcctggtgtcatctaccggctcgacgatccgaaat
cggcgacgctcatcttcgactctggcaaagctgtctgcaccggcgcccaatctgtcgacgacgtccacgacgccatcagt
atcgtcgtcgaagacctccgcgacctcggtatcgacatcccgcccagtccgccggttcacgtccagaatatcgtctgcag
cggcagtctggaccaagatctgaacctgaacgcgatcgccatcggactcggcctcgaagacgtcgaatacgaacccgaac
agttccccggcctcgtctatcgcctcaacgaccccgatgttgtggtgttgttgttcggcagcggcaaactcgtcatcacg
ggtgggagcaacccagacgacgcccaccacgcactcgagatcatccatgagcggctcaccgacctcggcctcctcgagta
a
pI3.8
MW (k)19.88101
Translation (186 aa, Edit)>tbpD|5163|gene
MSTLTDTIQIENVVASTDLSQELALEQLATDLPGAEYNPGDFPGVIYRLDDPKSATLIFDSGKAVCTGAQSVDDVHDAIS
IVVEDLRDLGIDIPPSPPVHVQNIVCSGSLDQDLNLNAIAIGLGLEDVEYEPEQFPGLVYRLNDPDVVVLLFGSGKLVIT
GGSNPDDAHHALEIIHERLTDLGLLE
TbpD coordinates the expression of over 10% of genes in the Halobacterium NRC-1 genome together with TfbA, consistent with the role of these two transcription factors in gene regulation. Some of the regulated genes code for heat shock proteins and their deletion leads to a temperature sensitive phenotype. See Coker and DasSarma [BMC Genetics 2007 Sep 24;8:61](https://www.ncbi.nlm.nih.gov/pubmed/17892563). This gene was formerly labeled as a chp 04/02 (chp BLAST analysis).